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Advances in Male Mediated Developmental Toxicity NEW Experimental Medicine V 518

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Item specifics

Condition
Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitionsopens in a new window or tab
Book Title
Advances in Male Mediated Developmental Toxicity
Narrative Type
Nonfiction
Subject
Medicine
Intended Audience
Adults
Genre
Health, Treatments & Medicine
Subjects
Health, Treatments & Medicine
ISBN
9780306474804
Category

About this product

Product Identifiers

Publisher
Springer
ISBN-10
0306474808
ISBN-13
9780306474804
eBay Product ID (ePID)
2424228

Product Key Features

Number of Pages
Xxvii, 300 Pages
Publication Name
Advances in Male Mediated Developmental Toxicity
Language
English
Subject
Reproductive Medicine & Technology, Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology), Life Sciences / Genetics & Genomics, Life Sciences / Developmental Biology, Genetics
Publication Year
2003
Type
Textbook
Subject Area
Science, Medical
Author
Barbara F. Hales
Series
Advances in Experimental Medicine and Biology Ser.
Format
Hardcover

Dimensions

Item Weight
50.1 Oz
Item Length
9.3 in
Item Width
6.1 in

Additional Product Features

Intended Audience
Scholarly & Professional
LCCN
2002-040969
Dewey Edition
21
Series Volume Number
518
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
616.6/071
Table Of Content
Gender-Specificity of Gamete Susceptibilities to Exposures.- 1. Female-Specific Reproductive Toxicities Following Preconception Exposure to Xenobiotics.- 2. Overview of Male Mediated Developmental Toxicity.- Exposures and Effects: Occupational and Environmental.- 3. Epidemiologic Evidence on Biological and Environmental Male Factors in Embryonic Loss.- 4. Mechanisms of Male Mediated Developmental Toxicity Induced by Lead.- 5. Paternal Exposure to Known Mutagens and Health of the Offspring:.- 6. FISH (Fluorescence In Situ Hybridization) to Detect Effects of Smoking, Caffeine, and Alcohol on Human Sperm Chromosomes.- Markers of Sperm Damage and Germ Line Genotoxicity.- 7. Sperm Nuclear DNA Damage in the Human.- 8. The Human Spermatozoon--Not Waving but Drowning.- 9. Model Systems for Studying Germ Cell Mutagens: From Flies to Mammals.- 10. Germline Mutation Induction at Mouse and Human Tandem Repeat DNA Loci.- 11. PAINT/DAPI Analysis of Mouse Zygotes to Detect Paternally Transmitted Chromosomal Aberrations.- Exposures and Effects: Causes of Cancer and Consequences of Treatment.- 12. Paternal Occupation and Childhood Cancer.- 13. Radiation and Malformations in a Murine Model.- 14. Mechanisms of Action of Cyclophosphamide as a Male-Mediated Developmental Toxicant.- 15. Chromosome Abnormalities in Human Sperm.- Pregnancy Outcome.- 16. Distinguishing between Fertilization Failure and Early Pregnancy Loss when Identifying Male-Mediated Adverse Pregnancy Outcomes.- 17. ICSI, Male Pronuclear Remodeling and Cell Cycle Checkpoints.- 18. Increased Incidence of Malformations in the Offspring of Male Mice Prenatally Exposed to Synthetic Estrogens.- Strategies for Prevention.- 19. Implications of Research in Male-Mediated Developmental Toxicity to Clinical Counsellors, Regulators,and Occupational Safety Officers.- 20. Restoration of Spermatogenesis after Exposure to Toxicants: Genetic Implications.- Future Directions.- 21. Epigenetics: Role of Germ Cell Imprinting.- 22. Efficiency and Safety of Animal Cloning.- Workshop Reports.- 23. Integrating New Tests of Sperm Genetic Integrity into Semen Analysis: Breakout Group Discussion.- 24. Risk Assessment.- 25. Study Designs for the Assessment of Male Mediated Developmental Toxicity.- 26. Translational Research in Male Mediated Developmental Toxicity.- 285.- 287.
Synopsis
It is nearly a decade since the first Male Mediated Developmental Toxicity conference was held in Pittsburgh. The continuing public/scientific interest, growing amounts of animal data, introduction of innovative technologies, and increasing quantity of human epidemiological studies all suggest that male-mediated developmental toxicity is of major concern. A number of researchers concluded that a Second International Confer- ence on Male Mediated Developmental Toxicity was necessary. The ensuing volume is particularly timely because it impacts on areas of special emphasis in many countries, with respect to children's and reproductive health, as well as to basic molecular mecha- nisms of environmental insult, and genetic susceptibility and predisposition. The Programme and Local Organizing Committee, composed of Barbara Hales (Chair, McGill University), BernardRobaire (McGill University), Daniel G. Cyr (INRS/ Armand Frappier), Jacquetta M. Trasler (McGill University), Andrew F. Olshan (Uni- versity of North Carolina), Sally Perreault Damey (US EPA), Donald R. Mattison (March of Dimes), and Jan M. Friedman (University of British Columbia), spent over two years identifying individuals who had made key contributions in this field over the past decade and planning various aspects of the meeting. The meeting was held in Montreal in June 2001. A total of 132 persons, coming from five continents and representing some 18countries, took an active role in the proceedings. The conference was considered by all attendees to be a rousing success. Important discussions were held in the four break-out sessions, with a preliminary set of recommendations for action being presented by each panel., It is nearly a decade since the first Male Mediated Developmental Toxicity conference was held in Pittsburgh. The continuing public/scientific interest, growing amounts of animal data, introduction of innovative technologies, and increasing quantity of human epidemiological studies all suggest that male-mediated developmental toxicity is of major concern. A number of researchers concluded that a Second International Confer­ ence on Male Mediated Developmental Toxicity was necessary. The ensuing volume is particularly timely because it impacts on areas of special emphasis in many countries, with respect to children's and reproductive health, as well as to basic molecular mecha­ nisms of environmental insult, and genetic susceptibility and predisposition. The Programme and Local Organizing Committee, composed of Barbara Hales (Chair, McGill University), BernardRobaire (McGill University), Daniel G. Cyr (INRS/ Armand Frappier), Jacquetta M. Trasler (McGill University), Andrew F. Olshan (Uni­ versity of North Carolina), Sally Perreault Damey (US EPA), Donald R. Mattison (March of Dimes), and Jan M. Friedman (University of British Columbia), spent over two years identifying individuals who had made key contributions in this field over the past decade and planning various aspects of the meeting. The meeting was held in Montreal in June 2001. A total of 132 persons, coming from five continents and representing some 18countries, took an active role in the proceedings. The conference was considered by all attendees to be a rousing success. Important discussions were held in the four break-out sessions, with a preliminary set of recommendations for action being presented by each panel.
LC Classification Number
QH491-492

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