Death Receptors in Cancer Therapy by Wafik S. El-Deiry (English) Hardcover Book

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eBay item number:267016211164
Last updated on Oct 27, 2025 07:13:19 MYTView all revisionsView all revisions

Item specifics

Condition
Like New: A book in excellent condition. Cover is shiny and undamaged, and the dust jacket is ...
Book Title
Death Receptors in Cancer Therapy
ISBN-13
9781588291721
ISBN
9781588291721
Category

About this product

Product Identifiers

Publisher
Humana Press
ISBN-10
1588291723
ISBN-13
9781588291721
eBay Product ID (ePID)
30231890

Product Key Features

Number of Pages
Xii, 374 Pages
Language
English
Publication Name
Death Receptors in Cancer Therapy
Publication Year
2004
Subject
Oncology
Type
Textbook
Author
Beverly A. Teicher
Subject Area
Medical
Series
Cancer Drug Discovery and Development Ser.
Format
Hardcover

Dimensions

Item Weight
69.1 Oz
Item Length
10 in
Item Width
7 in

Additional Product Features

Intended Audience
Scholarly & Professional
LCCN
2004-006682
Reviews
From the reviews: "The book is resourceful for both basic scientists and clinicians, who are interested in developing targeted therapies for cancer. a? the book is a valuable tool for researchers as well as to those of us involved in teaching apoptosis to undergraduate and graduate students." (Harikrishna Nakshatri, Leukemia Research, 2005), From the reviews: "The book is resourceful for both basic scientists and clinicians, who are interested in developing targeted therapies for cancer. ... the book is a valuable tool for researchers as well as to those of us involved in teaching apoptosis to undergraduate and graduate students." (Harikrishna Nakshatri, Leukemia Research, 2005), From the reviews:"The book is resourceful for both basic scientists and clinicians, who are interested in developing targeted therapies for cancer. … the book is a valuable tool for researchers as well as to those of us involved in teaching apoptosis to undergraduate and graduate students." (Harikrishna Nakshatri, Leukemia Research, 2005)
Dewey Edition
22
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
571.9/36
Table Of Content
Mammalian Cell Death Pathways.- Resistance to Apoptosis in Cancer Therapy.- Structures of TNF Receptors and Their Interactions With Ligands.- Death Receptor Signaling in Embryonic Ectodermal Development.- Adaptor Proteins in Death Receptor Signaling.- Caspase Activation by the Extrinsic Pathway.- Death Signaling and Therapeutic Applications of TRAIL.- Death Receptor Mutations.- Regulation of Death Receptors.- Regulation of Trail Receptor Expression in Human Melanoma.- Regulation of Death Receptors by Synthetic Retinoids.- Role of p53 in Regulation of Death Receptors.- Proapoptotic Gene Silencing Via Methylation in Human Tumors.- Regulation of Death Receptor-Induced Apoptosis by NF-?B and Interferon Signaling Pathways.- TRAIL in Cancer Therapy.- Expression and Regulation of Death Receptors in Multiple Myeloma and Prostate Carcinoma.- Regulation of TRAIL-Induced Apoptosis by Transcriptional Factors.- Sensitizing Tumor Cells by Targeting Death Receptor Signaling Inhibitors.- Ceramide, Ceramidase, and FasL Gene Therapy in Prostate Cancer.- Gene Therapy Targeting Receptor-Mediated Cell Death to Cancers.- Combination of Chemotherapy and Death Ligands in Cancer Therapy.
Synopsis
reviews the death ligands, death receptor pathways and their alterations in human cancer; covers novel emerging signal transduction cascades and their complex regulation and cross-talk with other intracellular signaling pathways that impact on cell survival; includes strategies for the use of death receptor pathways to develop diagnostic and therapeutic strategies for cancer., An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.
LC Classification Number
RC254-282

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